Methods in Bioinformatics

Content:

In Professor Dinu’s first lecture, he introduced the 4 fundamental sources of bioinformatics data: DNA, mRNA, protein and metabolite. As the researches of these data go on, some “omes ” are introduced: Genome, Transcriptome, Proteome and Metabolome. Biomarkers are gathered from the biological information flow: DNA->RNA->Protein.

In the second lecture, Dr. Dinu gave an overview of the Bioinformatics techniques. The mathematics devotes a lot to the bioinformatics data analysis, including statistics and machine learning which used to be the topic in last classes. For sequence alignment, BLAST is the most popular tool. The purpose of sequence alignment is to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences.


Posted by  Xiaoxiao